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Hospital Innovation Programs Directory

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Health system intelligence profile

The Pearl

Advocate Health (Atrium Health)

Last reviewed August 30, 2026

Intelligence summary

Program at a Glance

Program mandate
The Pearl is Advocate Health and Atrium Health's innovation district in Charlotte's historic Brooklyn neighborhood, launched June 2, 2025 in partnership with Wexford Science & Technology and Ventas. It is designed as a physical ecosystem that co-locates medical education, research, industry partners and health technology companies so that surgeons, scientists, startups and students work in proximity.
Organizational model
Nonprofit
Location
Charlotte, North Carolina
Program types
Innovation center
Commercialization pathways
InvestmentStrategic partnership
Focus areas
Clinical
Public scale or maturity signals

Established 2025

Documented successes: Launched June 2, 2025 with a first phase spanning more than 700,000 square feet (Atrium Health newsroom); Projected over 15 years to generate 5,500 on-site jobs and 11,500 total regional jobs; Anchored by the Wake Forest University School of Medicine Charlotte campus, Charlotte's first four-year medical school; IRCAD North America established its exclusive North American headquarters for advanced surgical training in the district; Siemens Healthineers opened a U.S. Experience Center there; Developed as a public-private partnership with Wexford Science & Technology and Ventas

Official engagement route
Program website ↗Health system website ↗
Last reviewed
August 30, 2026

Mandate and remit

What This Program Does

The Pearl is Advocate Health and Atrium Health's innovation district in Charlotte's historic Brooklyn neighborhood, launched June 2, 2025 in partnership with Wexford Science & Technology and Ventas. It is designed as a physical ecosystem that co-locates medical education, research, industry partners and health technology companies so that surgeons, scientists, startups and students work in proximity. Its anchors are the Wake Forest University School of Medicine Charlotte campus, Charlotte's first four-year medical school, and IRCAD North America, the exclusive North American headquarters of the advanced surgical training institute. Siemens Healthineers operates a U.S. Experience Center in the district. Outside companies engage The Pearl as tenants, training partners and research collaborators rather than through an investment vehicle.

Areas of Focus

Clinical

Commercialization Pathways

These routes appear in the program's sourced public record.

Publicly Reported Outcomes

  • Documented successes

    Launched June 2, 2025 with a first phase spanning more than 700,000 square feet (Atrium Health newsroom); Projected over 15 years to generate 5,500 on-site jobs and 11,500 total regional jobs; Anchored by the Wake Forest University School of Medicine Charlotte campus, Charlotte's first four-year medical school; IRCAD North America established its exclusive North American headquarters for advanced surgical training in the district; Siemens Healthineers opened a U.S. Experience Center there; Developed as a public-private partnership with Wexford Science & Technology and Ventas

Contact the Program

Use the program's published contact route for partnership, licensing, innovation, or program inquiries.

Official contact page
Open contact page ↗

Related Programs

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Same state · Same program type · Same commercialization route

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Winston-Salem, North Carolina

Advocate Health (Wake Forest University School of Medicine / Atrium Health Wake Forest Baptist)

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The Center for Healthcare Innovation is the implementation-focused innovation engine inside Atrium Health Wake Forest Baptist, built around the premise that it takes an average of 17 years to move medical discoveries into mainstream care and that the gap can be narrowed.

Innovation centerAcceleratorStrategic partnershipClinicalWorkforce

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Durham, North Carolina

Duke University Health System (Duke Health)

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The Duke Institute for Health Innovation (DIHI) is Duke Health's central innovation engine, created to catalyze transformative innovations in health and healthcare and to cultivate a community of innovation and entrepreneurship across Duke University and the health enterprise.

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Durham, North Carolina

Duke University Health System / Duke University School of Nursing

Health Innovation Lab (HILab) and Office of the Chief Nurse Innovation Officer

The Health Innovation Lab is a 20,000-plus-square-foot facility at the Duke University School of Nursing, adjacent to Duke University Hospital, that advances nurse-led models of care and translates clinical ideas into practice.

Innovation centerNursing innovationAcceleratorLicenseStrategic partnershipClinicalMedical deviceDigital

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Editorially verified · Reviewed August 30, 2026

Same state · Same program type · Same commercialization route

Winston-Salem, North Carolina

Novant Health

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Novant Health Enterprises is an independent business division launched by Novant Health in March 2022 to incubate, acquire and commercialize healthcare businesses rather than to make passive minority investments.

Venture studioInnovation centerSpinoutAcquisitionClinicalDigitalOperational

Nonprofit

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Editorially verified · Reviewed August 30, 2026

Same state · Same program type · Same commercialization route

Winston-Salem, North Carolina

Novant Health

Novant Health Institute of Innovation & Artificial Intelligence

Novant Health opened its Institute of Innovation & Artificial Intelligence in Winston-Salem, North Carolina on June 5, 2019 to apply AI to personalized patient care across prediction, prevention, diagnosis and treatment.

Innovation centerStrategic partnershipClinicalArtificial intelligenceDigital

Nonprofit

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Reviewed August 30, 2026

Sources and Updates

Reviewed August 30, 2026. External source links open in a new tab.

  1. The Pearl official source atriumhealth.org. Accessed August 30, 2026.
  2. The Pearl source 2 advocatehealth.org. Accessed August 30, 2026.
  3. The Pearl source 3 atriumhealth.org. Accessed August 30, 2026.

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