These profiles are based in Illinois according to official program or system locations. A health system may also operate facilities in other states. Inclusion is not an endorsement.
Chicago, Illinois
Advocate Aurora Enterprises
Advocate Aurora Enterprises was the investment and business-building arm of Advocate Aurora Health, now part of Advocate Health, the third-largest nonprofit health system in the country.
Venture fundVenture studioSpinoutInvestmentClinicalDigitalConsumer
Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Chicago, Illinois
Innovate2Impact (I2I) Program
Innovate2Impact is the innovation and intellectual property program of Lurie Children's and the Stanley Manne Children's Research Institute, created to bridge the gap between discovery and usable products and technologies.
Technology transferInnovation centerLicenseStrategic partnershipClinicalPediatricWorkforce
Children's · Nonprofit
Read the intelligence briefReviewed August 30, 2026
Chicago, Illinois
Virtually Integrated Care (VIC)
Virtually Integrated Care is CommonSpirit Health's system-wide virtual nursing program, in which remote nurses support bedside teams with admissions, discharges, documentation, education and second-nurse verification.
Nursing innovationStrategic partnershipClinicalMedical deviceDigital
Nonprofit
Read the intelligence briefReviewed August 30, 2026
Chicago, Illinois
CommonSpirit Ventures
CommonSpirit Ventures is the strategic investment arm of CommonSpirit Health, one of the largest nonprofit health systems in the United States, and describes itself as one of the longest continuously operating health system venture funds.
Venture fundInvestmentClinicalArtificial intelligenceOperational
Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Evanston, Illinois
Endeavor Health Innovation
Endeavor Health Innovation is the system's front door for co-developing, piloting and scaling new health technologies inside a nine-hospital Chicago-area system.
Innovation centerStrategic partnershipClinicalArtificial intelligenceDigital
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Evanston, Illinois
Innovation & New Ventures Office (INVO)
Innovation and New Ventures Office (INVO) supports the transition of Northwestern University research into practical applications, including work from the Feinberg School of Medicine and Northwestern Medicine clinicians.
Technology transferVenture studioEntrepreneurshipLicenseSpinoutClinicalWorkforce
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Peoria, Illinois
OSF Innovation
OSF Innovation is the enterprise innovation function of OSF HealthCare, combining multidisciplinary internal teams with external partners to identify, develop and implement healthcare solutions.
Innovation centerVenture fundAcceleratorInvestmentStrategic partnershipClinical
Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Peoria, Illinois
OSF Ventures (OSF Innovation)
OSF Ventures is the venture investment arm of OSF HealthCare and sits inside OSF Innovation, the system's broader innovation organization.
Venture fundInnovation centerAcceleratorInvestmentStrategic partnershipClinicalMedical deviceTherapeutics
Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Peoria, Illinois
Nursing Innovation Lab and Nursing Innovation Fellowship
OSF HealthCare runs a dedicated Nursing Innovation Lab inside OSF Innovation that develops nurse-led solutions to improve care delivery and nursing workflow.
Innovation centerNursing innovationAcceleratorStrategic partnershipClinicalWorkforceOperational
Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Chicago, Illinois
Innovation + Technology Commercialization (ITeC) Office
The Innovation + Technology Commercialization (ITeC) Office sits within RUSH Legal and is responsible for protecting and managing intellectual property generated through Rush University research.
Technology transferLicenseInvestmentClinical
Academic · Nonprofit
Read the intelligence briefReviewed August 30, 2026
Chicago, Illinois
Office of Technology Management (OTM) — UI Health
The Office of Technology Management commercializes research and educational activities at the University of Illinois Chicago, including discoveries from the Colleges of Medicine, Pharmacy, Nursing and Dentistry that sit alongside the UI Health hospital and clinics.
Technology transferLicenseStrategic partnershipClinicalTherapeuticsWorkforce
Academic · Nonprofit
Read the intelligence briefReviewed August 30, 2026
Chicago, Illinois
Polsky Center for Entrepreneurship and Innovation
The Polsky Center for Entrepreneurship and Innovation houses both the University of Chicago's technology commercialization function and its startup acceleration programs, including biomedical and health technologies from UChicago Medicine.
Innovation centerAcceleratorTechnology transferLicenseInvestmentClinical
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026