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Health system intelligence profile

Polsky Center for Entrepreneurship and Innovation

University of Chicago / UChicago Medicine

Editorially verified · Last reviewed August 30, 2026

Intelligence summary

Program at a Glance

Program mandate
The Polsky Center for Entrepreneurship and Innovation houses both the University of Chicago's technology commercialization function and its startup acceleration programs, including biomedical and health technologies from UChicago Medicine. It manages invention disclosure and IP licensing while running accelerators, incubator space and the Edward L.
Organizational model
Academic · Nonprofit
Location
Chicago, Illinois
Program types
Innovation centerAcceleratorTechnology transferVenture fundEntrepreneurship
Commercialization pathways
LicenseInvestmentStrategic partnership
Focus areas
Clinical
Public scale or maturity signals

The Polsky Center for Entrepreneurship and Innovation houses both the University of Chicago's technology commercialization function and its startup acceleration programs, including biomedical and health technologies from UChicago Medicine. It manages invention disclosure and IP licensing while running accelerators, incubator space and the Edward L. Kaplan New Venture Challenge. Polsky operates the Polsky Exchange co-working space, the UChicago Science Incubator and a San Francisco satellite. It also administers deep-tech venture programs in partnership with other Midwestern universities.

Documented successes: 231 invention disclosures and 30 IP licenses issued with $22 million in licensing revenue (2024-2025); $2.1 million distributed through the 30th annual Edward L. Kaplan New Venture Challenge; 40 startups presenting at Midwest Deep Tech Demo Day; launched Third Coast Foundry across eight Midwestern universities

Official engagement route
Program website ↗Health system website ↗
Last reviewed
August 30, 2026

Mandate and remit

What This Program Does

The Polsky Center for Entrepreneurship and Innovation houses both the University of Chicago's technology commercialization function and its startup acceleration programs, including biomedical and health technologies from UChicago Medicine. It manages invention disclosure and IP licensing while running accelerators, incubator space and the Edward L. Kaplan New Venture Challenge. Polsky operates the Polsky Exchange co-working space, the UChicago Science Incubator and a San Francisco satellite. It also administers deep-tech venture programs in partnership with other Midwestern universities.

Areas of Focus

Clinical

Commercialization Pathways

These routes appear in the program's sourced public record.

Venture Investment and Company Creation

Fund or office: Polsky Center for Entrepreneurship and Innovation

The Polsky Center for Entrepreneurship and Innovation houses both the University of Chicago's technology commercialization function and its startup acceleration programs, including biomedical and health technologies from UChicago Medicine. It manages invention disclosure and IP licensing while running accelerators, incubator space and the Edward L. Kaplan New Venture Challenge. Polsky operates the Polsky Exchange co-working space, the UChicago Science Incubator and a San Francisco satellite. It also administers deep-tech venture programs in partnership with other Midwestern universities.

Publicly Reported Outcomes

  • Documented successes

    231 invention disclosures and 30 IP licenses issued with $22 million in licensing revenue (2024-2025); $2.1 million distributed through the 30th annual Edward L. Kaplan New Venture Challenge; 40 startups presenting at Midwest Deep Tech Demo Day; launched Third Coast Foundry across eight Midwestern universities

Contact the Program

Use the program's published contact route for partnership, licensing, innovation, or program inquiries.

Program phone
773-834-4525
Official contact page
Open contact page ↗

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Sources and Updates

Reviewed August 30, 2026. External source links open in a new tab.

  1. Polsky Center for Entrepreneurship and Innovation official source polsky.uchicago.edu. Accessed August 30, 2026.
  2. Polsky Center for Entrepreneurship and Innovation source 2 polsky.uchicago.edu. Accessed August 30, 2026.

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