These profiles are based in Pennsylvania according to official program or system locations. A health system may also operate facilities in other states. Inclusion is not an endorsement.
Pittsburgh, Pennsylvania
AlphaLab Health
AlphaLab Health is a healthcare and life sciences startup accelerator launched in 2020 as a partnership between Allegheny Health Network, Highmark Health and Innovation Works, with support from Pittsburgh-area universities, corporations and foundations.
AcceleratorVenture fundEntrepreneurshipInvestmentStrategic partnershipClinicalMedical deviceTherapeutics
Nonprofit
Read the intelligence briefPartially verified · Reviewed August 30, 2026
Philadelphia, Pennsylvania
Innovation Ventures
Children's Hospital of Philadelphia publishes a pediatric commercialization pathway that has been reorganized over the past decade.
Technology transferEntrepreneurshipVenture fundLicenseSpinoutPediatricClinicalTherapeutics
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Danville, Pennsylvania
Geisinger Ventures
Geisinger Ventures is the for-profit venture arm of Geisinger, the integrated health system and health plan serving 42 counties in central and northeastern Pennsylvania.
Venture fundTechnology transferLicenseInvestmentClinicalOperational
Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Danville, Pennsylvania
Steele Institute for Health Innovation
The Steele Institute for Health Innovation is Geisinger's central innovation body, structured as a hub that coordinates nine internal development partner teams rather than as a single lab.
Innovation centerStrategic partnershipClinicalArtificial intelligenceDigital
Nonprofit
Read the intelligence briefReviewed August 30, 2026
Pittsburgh, Pennsylvania
Highmark Ventures
Highmark Ventures is the corporate venture capital arm of Highmark Health, the Pittsburgh-based integrated delivery and financing organization that owns Allegheny Health Network and the Highmark health plans.
Venture fundInvestmentStrategic partnershipClinicalTherapeuticsWorkforce
Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Philadelphia, Pennsylvania
Jefferson Innovation
Jefferson Innovation is the entrepreneurial and commercialization organization spanning Jefferson Health and Thomas Jefferson University.
Innovation centerTechnology transferAcceleratorLicenseStrategic partnershipClinicalWorkforce
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Philadelphia, Pennsylvania
Jefferson Ventures
Jefferson Ventures is the commercialization hub for Thomas Jefferson University and Jefferson Health, connecting clinicians, scientists and students with industry and strategic collaborators.
Technology transferVenture studioInnovation centerLicenseSpinoutClinicalWorkforce
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Philadelphia, Pennsylvania
JeffSolves MedTech / Health Design Lab
JeffSolves MedTech is a transdisciplinary medical device innovation program run through Jefferson's Health Design Lab that pairs medical students and clinicians with industrial design and textile design students.
Physician innovationEntrepreneurshipInnovation centerClinicalMedical deviceWorkforce
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Wynnewood, Pennsylvania
Lankenau Institute for Medical Research
The Lankenau Institute for Medical Research (LIMR) is Main Line Health's biomedical research institute, founded in 1927 and based at Lankenau Medical Center in Wynnewood, Pennsylvania.
Innovation centerTechnology transferEntrepreneurshipLicenseClinicalMedical deviceTherapeutics
Nonprofit
Read the intelligence briefReviewed August 30, 2026
Philadelphia, Pennsylvania
Innovation Accelerator Program
Penn Medicine's Center for Health Care Innovation publishes the Innovation Accelerator Program (IAP) as a structured pathway for faculty and staff developing, testing, and implementing new approaches to health-care delivery and patient outcomes.
Innovation centerAcceleratorEntrepreneurshipClinicalOperationalDigital
Academic
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Philadelphia, Pennsylvania
Innovation Accelerator Program, Center for Health Care Transformation and Innovation
Penn Medicine's Innovation Accelerator Program supports faculty physicians and staff who want to design, test and scale new approaches to healthcare delivery.
Physician innovationAcceleratorInnovation centerStrategic partnershipClinicalOperational
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Philadelphia, Pennsylvania
Penn Health-Tech
Penn Health-Tech is a University of Pennsylvania center, established around 2017, that connects innovators across Penn Medicine and Penn's engineering and business schools to advance medical devices and healthcare technology.
AcceleratorInnovation centerEntrepreneurshipInvestmentStrategic partnershipClinicalMedical deviceWorkforce
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Hershey, Pennsylvania
Center for Medical Innovation (CMI)
The Center for Medical Innovation supports Penn State College of Medicine faculty, researchers and learners in moving medical innovations toward commercialization.
Innovation centerTechnology transferPhysician innovationLicenseInvestmentClinical
Academic · Nonprofit
Read the intelligence briefReviewed August 30, 2026
Hershey, Pennsylvania
Office of Nursing Research and Innovation — Penn State Health Milton S. Hershey Medical Center
The Office of Nursing Research and Innovation at Penn State Health Milton S.
Nursing innovationStrategic partnershipClinicalWorkforceOperational
Nonprofit
Read the intelligence briefReviewed August 30, 2026
Philadelphia, Pennsylvania
Office of Technology Commercialization and Business Development
Temple University's Office of Technology Commercialization and Business Development is the integrated hub through which entrepreneurs and industry find partnership opportunities in Temple research, including work from the Lewis Katz School of Medicine and Temple Health.
Technology transferEntrepreneurshipLicenseSpinoutClinicalTherapeuticsOperational
Academic · Nonprofit
Read the intelligence briefReviewed August 30, 2026
Philadelphia, Pennsylvania
Penn Nursing Innovation Accelerator
The Penn Nursing Innovation Accelerator funds and coaches nurse-originated health care solutions at the earliest stage.
AcceleratorNursing innovationEntrepreneurshipStrategic partnershipClinicalMedical deviceTherapeutics
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Philadelphia, Pennsylvania
Johnson & Johnson Nurse Innovation Fellowship (JJNIF)
The Johnson & Johnson Nurse Innovation Fellowship is a one-year, team-based fellowship for chief nursing officers, nurse executives and senior nurse leaders drawn from U.S.
Nursing innovationEntrepreneurshipAcceleratorStrategic partnershipClinicalWorkforce
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026
Pittsburgh, Pennsylvania
UPMC Enterprises
UPMC Enterprises is the official innovation, commercialization, and venture capital arm of UPMC.
Venture fundVenture studioInnovation centerInvestmentSpinoutTherapeuticsDiagnosticsDigital
Academic · Nonprofit
Read the intelligence briefEditorially verified · Reviewed August 30, 2026